From USD $59.00

Enjoy the feeling of deep hydration, comfort, and repair with this intensive moisture infusion. Dp Dermaceuticals HYLA ACTIVE™ is a wonder serum that reduces the appearance of fine lines and pores for a flawless finish, while also diffusing the appearance of redness and inflammation. It contains the highest concentration of our revolutionary HylaFuse™ Technology to deliver Hyaluronic Acid (HA) to optimal skin levels.

  • Potent Hydrating HylaFuse HA
  • Absorb HA
    150% More Effectively
  • Reduces Signs of Ageing

From USD $59.00

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Dp Dermaceutical’s breakthrough Hyaluronic Acid (HA) formulation, HylaFuse, delivers biologically active HA and other active ingredients deeper into your skin.

Dp Dermaceuticals HYLA ACTIVE contains a potent strength of HylaFuse for intense nourishment and hydration, and is proven to be absorbed 150% more effectively into the skin than other forms of HA. The HylaFuse in HYLA ACTIVE encapsulates Zinc and Vitamin B5 to deliver these restorative active ingredients deeper into the skin for up to 8 hours after application.

HYLA ACTIVE is a multifunctional serum that’s Dermapen-approved for use during and immediately following microneedling procedures. It’s a popular Meso-Glide™ serum that can be mixed 1:1 with other approved serums such as BRITE LITE™ or ANTIOXIDANT COCKTAIL™ to target your individual skin concerns. We like to say it forms a ‘second skin’ as it provides a protective hydration layer, which is particularly beneficial following rejuvenation procedures, such as Dermapen microneedling.

Particularly effective on dehydrated skin, HYLA ACTIVE helps reduce the appearance of fine lines and pores for a flawlessly smooth finish.

Key Benefits

  • Forms a ‘second skin’ to deliver an immediate effect
  • Infuses a feeling of deep hydration, comfort and repair
  • Reduces and diffuses the appearance of visible redness and inflammation
  • Promotes regeneration and repair for younger-looking skin
  • Plumps and smooths the signs of environmental ageing
  • Helps reduce the appearance of fine lines and pores for a flawless, smooth finish

How to Use

Daily Skin Care Routine

Apply after cleansing the skin with TRI-PHASE CLEANSER™ and exfoliating with MICRO DERM EXFOLIANT™.

  1. Apply 2–3 pumps of Dp Dermaceuticals HYLA ACTIVE to dry skin.
  2. Massage lightly into the skin until absorbed.
  3. Follow with Dp Dermaceuticals corrector products for your skin concern.

Dermapen Microneedling Procedures

May be applied during Dermapen procedures as a Meso-Glide to create a smooth, gliding medium.

  1. Use a thin coat of Dp Dermaceuticals HYLA ACTIVE during microneedling as a Meso-Glide treatment medium. Apply to one section at a time.
  2. Perform Dermapen microneeling procedure as per instructions.
  3. HYLA ACTIVE may be applied immediately after microneedling with light pressing motions until absorbed.
  4. Follow with prescribed Dp Dermaceuticals products for your skin concerns.

For extra hydration, use HYLA ACTIVE for the 5 days following a procedure. Apply HYLA ACTIVE before other Dp Dermaceuticals products.

Performance Ingredients

HylaFuse Complex

A triple weighted Hyaluronic Acid complex that effortlessly absorbs into the skin to promote maximum hydration moisture infusion and long-lasting comfort.


A potent anti-inflammatory mineral that promotes wound healing, repair and collagen formation. The skin recovers faster and stronger when its integrity has been compromised.

Vitamin B5

An active vitamin necessary for tissue repair while re-fortifying barrier function. The complexion’s defences feel better equipped and protected.

Full Ingredient List

Water (Aqua), Sodium Hyaluronate @ 10mg/ml, Zinc PCA, Panthenol, Phenoxyethanol, Ethylhexylglycerin 

Accelerate your results with

Frequently bought with


Literally any of our other products! HYLA ACTIVE is a central product in our range that is hugely popular thanks to its versatility. It’s used as the Meso-Glide base for most Dermapen microneedling procedures due to its potent strength of hydrating HylaFuse—our signature Hyaluronic Acid formulation. Use at home with Dermapen HOME™ microneedling pen for outstanding results.

Dp Dermaceuticals HYLA ACTIVE restores harmony to all skin types and conditions, including aged, pigmented, sun-damaged, dehydrated, sensitive and problematic skin. Its intense moisturising properties revive dull, fatigued, roughened and dry skin.

HylaFuse contains 3 molecular sizes of Hyaluronic Acid (HA), the smallest of which can penetrate the deepest layers of the skin. HylaFuse is clinically proven to be absorbed 150% more effectively than other forms of HA. Dp Dermaceuticals products containing HylaFuse Complex continue delivering water and active ingredients up to 8 hours after application.

Our Meso-Glides are the products you apply topically to help the Dermapen move effortlessly across your skin. During the microneedling process, the active ingredients are infused (needled) into your skin for greater absorption and superior results.

You have to be careful when needling products into your skin. Our active Meso-Glide combinations have proven protocol outcomes. They are endorsed by thousands of practitioners around the globe, for safe, active ingredient infusion into the skin without risks of negative side effects.

Yes, we want you to feel completely confident at every step of your skin journey with us.

Our worry-free policy gives you 60 days to try any of our products purchased online. If you don’t see results return the products and we’ll arrange a refund (minus shipping and handling fees).

Yes, we absolutely do ship worldwide. Simply enter your preferred shipping address during the purchase process.

We love talking about your skin! Contact us to speak with an expert today.

Customer Reviews

3 reviews for HYLA ACTIVE
5.00 / 5

Write A Review
  1. Cindy J

    Another product from this company that is a must in a daily routine. It INSTANTLY hydrates the shin and leaves the softness only known when I touched a babies face, now I can say mine feels just as beautiful. Using this daily, but more so when using it for a dermapen4 or at home treatment, make such a difference that you simply cant go without it once you try the product.

  2. Mara

    HylaActive is my daily must. I apply under Vitamin Rich Repair in the mornings and under Retinal Active in the evenings. It gives me that extra feeling of instant hydration and plumps my skin immediately. Love it.

  3. Kristina Wolfe (verified owner)

    I use this during microneedling (obviously) and it feels nicer and my skin responds very well to this serum. I use a lot during treatments and I also like to use a little on dry skin between treatments. My only gripe is that it can ‘peel’ once it dries out (of you used a lot as you would immediately after treatments) and can cause itching. That is easily counteracted by moistening the skin and it goes back to being a lovely soothing goop. It’s very expensive like all the products but it’s a winner.

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